Product Details
Product Name:
– PROTAC BRAF-V600E degrader-1
Catalog Number:
– D65671
Field of Application:
– PROTAC BRAF-V600E degrader-1 is a potent PROTAC BRAF-V600E degrader with Kd value of 2.4 nM and 2 nM for BRAF and BRAF-V600E, respectively. PROTAC BRAF-V600E degrader-1 degrades BRAF-V600E via the ubiquitin-proteasome system (UPS). PROTAC BRAF-V600E degrader-1 can inhibit melanoma cell growth.
CAS:
– [2417296-84-3]
Formular:
– C48H54F2N10O10S
SMILES:
– S(C([H])([H])C([H])([H])C([H])([H])[H])(N([H])C1C([H])=C([H])C(=C(C=1F)N1C([H])=C(C2=C([H])N=C([H])N=C2[H])C2=C1C([H])=C([H])C(=N2)N(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C(C([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])N([H])C2=C([H])C([H])=C([H])C3C(N(C(C=32)=O)C2([H])C(N([H])C(C([H])([H])C2([H])[H])=O)=O)=O)=O)C([H])([H])C1([H])[H])F)(=O)=O
