Product Details
Product Name:
– RA-9
Catalog Number:
– D39255
Field of Application:
– RA-9 is a potent and selective proteasome-associated deubiquitinating enzymes (DUBs) inhibitor with favorable toxicity profile and anticancer activity. RA-9 blocks ubiquitin-dependent protein degradation without impacting 20S proteasome proteolytic activity. RA-9 selectively induces onset of apoptosis in ovarian cancer cell lines and primary cultures derived from donors. RA-9 induces endoplasmic reticulum (ER)-stress responses in ovarian cancer cells[1].
CAS:
– [919091-63-7]
Formular:
– C19H15N3O5
SMILES:
– C(/C1C=CC([N+](=O)[O-])=CC=1)=C1/CNC/C(=CC2C=CC([N+](=O)[O-])=CC=2)/C/1=O
