Product Details
Product Name:
– RLX-33
Catalog Number:
– D60330
Field of Application:
– RLX-33 is a potent, selective and blood-brain barrier (BBB) penetrant relaxin family peptide 3 (RXFP3) antagonist, also blocks relaxin-3-induced ERK1/2 phosphorylation, with IC50 values of 2.36 ?M for RXFP3, 7.82 and 13.86 ?M for ERK1 and ERK2 phosphorylation, respectively. RLX-33 can block the stimulation of food intake induced by the RXFP3-selective agonist R3/I5 in rats. RLX-33 can be used for the research of metabolic syndrome[1].
CAS:
– [2784577-71-3]
Formular:
– C24H19ClN4O4
SMILES:
– ClC1=CC=C(C2=NOC(C3=CC=C(NC(C4CC(N(CC5=CC=CO5)C4)=O)=O)C=C3)=N2)C=C1
