RMC-4550

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SKU D12051-10mg Category

Product Details

Product Name:

– RMC-4550

Catalog Number:

– D12051

Field of Application:

– RMC-4550 (RMC4550) is a potent, selective, allosteric inhibitor of SHP2 with IC50 of 0.58 nM (full-length SHP2 enzyme), suppresses pERK signaling in Calu-1 cells with IC50 of 7 nM.

CAS:

– [2172651-73-7]

Formular:

– C21H26Cl2N4O2

SMILES:

– ClC1=C(Cl)C(C2=NC(CO)=C(N3CCC4(CO[C@@H](C)[C@H]4N)CC3)N=C2C)=CC=C1

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