Product Details
Product Name:
– S-Ruxolitinib (INCB018424)
Catalog Number:
– D5199
Field of Application:
– S-Ruxolitinib is the chirality of INCB018424, which is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM, >130-fold selectivity for JAK1/2 versus JAK3. Phase 3.
CAS:
– [941685-37-6]
Formular:
– C17H18N6
SMILES:
– N#CC[C@@H](C1CCCC1)N2N=CC(C3=NC=NC4=C3C=CN4)=C2
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