Product Details
Product Name:
– Salermide
Catalog Number:
– D10002
Field of Application:
– Salermide is an inhibitor of SIRT1 and SIRT2, causing tumor-specific apoptotic cell death. In MOLT4 leukemia cells, salermide causes 90% apoptosis within 72 hours (IC50 ~ 20 ?M) by reactivating proapototic genes that are repressed by SIRT1.
CAS:
– [1105698-15-4]
Formular:
– C26H22N2O2
SMILES:
– OC1=CC=C2C=CC=CC2=C1/C=N/C3=CC(NC(C(C)C4=CC=CC=C4)=O)=CC=C3
