Product Details
Product Name:
– Samuraciclib
Catalog Number:
– D47269
Field of Application:
– Samuraciclib (CT7001) is a potent, selective, ATP-competitive and orally active CDK7 inhibitor, with an IC50 of 41 nM. Samuraciclib displays 45-, 15-, 230- and 30-fold selectivity over CDK1, CDK2 (IC50 of 578 nM), CDK5 and CDK9, respectively. Samuraciclib inhibits the growth of breast cancer cell lines with GI50 values between 0.2-0.3 ?M. Samuraciclib has anti-tumor effects.
CAS:
– [1805833-75-3]
Formular:
– C22H30N6O
SMILES:
– O[C@H]1CNCC[C@@H]1CNC1C=C(NCC2C=CC=CC=2)N2C(=C(C=N2)C(C)C)N=1
