Product Details
Product Name:
– Selpercatinib(LOXO-292)
Catalog Number:
– D11450
Field of Application:
– Selpercatinib is a RET kinase inhibitor extracted from patent WO2018071447A1, Compound Example 163, has an IC50 of 14.0 nM, 24.1 nM, and 530.7 nM for RET (WT), RET (V804M) , and RET (G810R), respectively. Antineoplastic activity.
CAS:
– [2152628-33-4]
Formular:
– C29H31N7O3
SMILES:
– N#CC1=C2C(C3=CC=C(N4CC(C5)N(CC6=CC=C(OC)N=C6)C5C4)N=C3)=CC(OCC(C)(O)C)=CN2N=C1
