Product Details
Product Name:
– TG101209
Catalog Number:
– D7317
Field of Application:
– TG101209 is a selective JAK2 inhibitor with IC50 of 6 nM, less potent to Flt3 and RET with IC50 of 25 nM and 17 nM, ~30-fold selective for JAK2 than JAK3, sensitive to JAK2V617F and MPLW515L/K mutations; TG101209 inhibit BRD4 activity with IC50 of 130 nM.
CAS:
– [936091-14-4]
Formular:
– C26H35N7O2S
SMILES:
– C(S(NC(C)(C)C)(=O)=O)1=CC=CC(NC2C(C)=CN=C(NC3=CC=C(N4CCN(C)CC4)C=C3)N=2)=C1
