Product Details
Product Name:
– THK-5470(THK5470)
Catalog Number:
– D46237
Field of Application:
– THK-5470(THK 5470), a monoamine oxidase-B (MAO-B) imaging probe, could be used for neurological diseases study. THK-5470 shows remarkably high binding affinity against MAO-B with an IC50 value of 4.2 nM, low binding affinity against tau with an IC50 value of 4462 nM. THK-5470 has high selective binding property and high affinity (from patent EP2019-846498).
CAS:
– [2410554-04-8]
Formular:
– C18H17FN2O2
SMILES:
– O(C[C@@H](CF)O)C1=CC=C2C(=C1)C=CC(C1=CN=C(C)C=C1)=N2
