Product Details
Product Name:
– Tinlorafenib
Catalog Number:
– D71910
Field of Application:
– Tinlorafenib (PF-07284890) (compound 10) is an orally active BRAF kinase inhibitor, with IC50s of 4.25 and 2.7 nM for BRAFV600E/V600K respectively. Tinlorafenib demonstrates CNS penetration and can be used in the research of BRAF-associated malignant and benign tumors of the CNS as well as extracranial malignancies[1].
CAS:
– [2573781-75-4]
Formular:
– C19H19ClF2N4O3S
SMILES:
– O=C1C2=C(C=CC(NC3=C(Cl)C(NS(=O)(CCCF)=O)=CC=C3F)=C2C)N=CN1C
