Product Details
Product Name:
– Tivozanib(AV-951)
Catalog Number:
– D5078
Field of Application:
– Tivozanib (AV-951, KRN-951) is a potent and selective VEGFR inhibitor for VEGFR1/2/3 with IC50 of 0.21 nM/0.16 nM/0.24 nM, and also inhibits PDGFR and c-Kit, low activity observed against FGFR-1, Flt3, c-Met EGFR and IGF-1R.
CAS:
– [475108-18-0]
Formular:
– C22H19ClN4O5
SMILES:
– O=C(NC1=CC=C(C=C1Cl)OC2=CC=NC3=CC(OC)=C(C=C23)OC)NC4=NOC(C)=C4
