Product Details
Product Name:
– UC-764865
Catalog Number:
– D70862
Field of Application:
– UC-764865 (UC764865) is a small-molecule inhibitor that targeted ubiquitin-conjugating enzyme UBE2N active site.UC-764865 blocks ubiquitination of innate immune- and inflammatory-related substrates in human AML cell lines.Inhibition of UBE2N function disrupted oncogenic immune signaling by promoting cell death of leukemic HSPCs while sparing normal HSPCs in vitro.
CAS:
– [2566480-63-3]
Formular:
– C18H16N2O2S
SMILES:
– C(C1=CC=C(OC)C=C1)(=O)/C=CSC1NC2=CC(C)=CC=C2N=1
