Product Details
Product Name:
– ZINC02092166
Catalog Number:
– D21852
Field of Application:
– ZINC02092166 is a novel potent, and selective small-molecule inhibitor for the ?-catenin/Tcf4 protein-protein interaction with Ki of 1.7 and 7.0 uM in AlphaScreen and FP assay (wild-type ?-catenin), respectively; remain affinity for muant catenin V511S, V511S/I569S and R469A with Ki of 20-50 uM; exhibits dual selectivity for ?-catenin/Tcf over ?-catenin/cadherin and ?-catenin/APC PPIs.
CAS:
– [354543-09-2]
Formular:
– C14H7N9O3
SMILES:
– O1N=C2C(N1)=NC1=C(C3C=CC=CC=3C1=N2)/N=N/C(C1C(N)=NON=1)=O
